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. 2014 Mar 17;9(3):e91934. doi: 10.1371/journal.pone.0091934

Figure 3. Regulatory protein-MAPK interaction strengths.

Figure 3

The binding strengths of each KIM-PTP (KIM peptides and KIM-containing MKBDs (in orange font), light blue; KIMKIS peptides, light purple; proteins, light pink) to p38α and ERK2 represented from weakest to tightest (largest Kd to smallest Kd) binding affinity; ‘†’ indicates values previously published [14], [15], [17], [18]. KIM-PTP:MAPK complexes determined to be extended using SAXS written in normal text; KIM-PTP:MAPK complexes determined to be compact written in italics; *, compact nature of the ERK2-PTPSL complex determined by Balasu et al. [24] and corroborated by ITC measurements (Table 1).