Image of a representative agarose gel of RT-PCR products after ethidium bromide staining is shown. Lanes 1, Normotensive rats; 2, untreated control SHRs; 3, SHRs treated with losartan (10 mg/kg); 4, SHRs treated with nicousamide at 15 mg/kg; 5, SHRs treated with nicousamide at 30 mg/kg and 6, SHRs treated with nicousamide at 45 mg/kg. *P<0.05 vs. untreated control SHRs group.