Table 2.

Summary of ethnobotanical uses versus measured biological activities of isolated secondary metabolites from; Combretaceae, Compositae, Connaraceae, Crassulaceae and Ebenaceae plant families

Plant family	Plant name	Use in traditional medicine	Part of plant studied	Active principle	Measured activity	Author and Reference
Combretaceae	Guiera senegalensis	Treatment of malaria, diarrhea, dysentery, venereal diseases and microbial infections	Leaves	28, 29 and 30	Antiplasmodial and antifungal activities	Iwalewa et al. [64], Ancolio et al. [65], Combier et al. [66], Silva and Gomez [67]
Compositae	Tithonia diversifola	Treatment of malaria, hepatitis, diabetes, malaria, pain, measles, chemoprevention and anti-Helicobacter pylori	Leaves	31	Antiplasmodial and anti-ulcer activities	Kuroda et al. [68], Castillo-Juárez et al. [69], Adebayo et al. [70], Goffin et al. [71], Sánchez-Mendoza et al. [72]
	Laggera pterodonta	Against insect attack, athlete’s foot, skin infections, pediatric malaria and wounds. Also used in treatment of hepatitis, arthritis, bronchitis and nephritis	Air-dried aerial part	32, 33, 34, 35 and 36	Antimicrobial Activity	Egharevba et al. [73]
Connaraceae	Byrsocarpus coccineus	Leaf decoction is used for the treatment of venereal diseases and as antidote to arrow poisoning and as remedy for pile, while the decoction of the whole plant is applied to swelling and tumours and also to arrest bleeding, the plant has also been reported as a remedy for diarrhea	Air-dried leaves	37, 38 and 39	Not tested	Ahmadu et al. [75]
Crassulaceae	Bryophyllum pinnatum	Treatment of ulcers, allergic inflammation and epilepsy	Dried whole plant	18, 40 and 41	Antibacterial activity	Ogungbamila et al. [76]
Ebenaceae	Diospyros mespiliformis	Leaf decoction used for whooping cough treatment and root extracts as worm expellants	Root	42	Cytotoxicity	Adeniyi et al. [83]