Table 2.
Activities of 11 antibiotics against two clinical strains (Ft6 and Ft24) of F. tularensis subsp. holarctica determined using a broth microdilution method and a dye uptake assay, respectively.
| MIC (μg/mL) | MIEC (μg/mL) | |||
|---|---|---|---|---|
| Ft6 | Ft24 | Ft6 | Ft24 | |
| Gentamicin | 0.25 | 0.5 | 2 | 2 |
| Ciprofloxacin | 0.032 | 0.032 | 0.064 | 0.064 |
| Levofloxacin | 0.064 | 0.064 | 0.064 | 0.064 |
| Moxifloxacin | 0.125 | 0.125 | 0.125 | 0.125 |
| Doxycycline | 0.5 | 1 | 0.5 | 0.5 |
| Erythromycin | 4 | 16 | 1 | 2 |
| Imipenem | >128 | >128 | >128 | >128 |
| Meropenem | >128 | >128 | >128 | >128 |
| Linezolid | 8 | 8 | 1 | 1 |
| Rifampicin | 0.5 | 0.5 | 0.5 | 0.5 |
| Daptomycin | >256 | >256 | >256 | >256 |
MIC, minimum inhibitory concentration; MIEC, minimum inhibitory extracellular concentration.