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Mean plasma corticosterone (ng/ml±SEM) response following ICV dexamethasone administration in running and sedentary mice following 28 days of wheel access. Dexamethasone 2 ng resulted in reduced corticosterone in running and sedentary mice. Administration of an intermediate dose of dexamethasone (750 ng/ml) did not produce divergent results (inset). *p<0.05, **p<0.01 in comparison with respective 0 ng dose.
