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. 2011 Dec;72(6):262–272. doi: 10.1016/j.curtheres.2011.11.003

Figure 3.

Figure 3

Effects of cyclosporine treatment on the diarrhea severity of the 5-fluorouracil (5-FU)–challenged animals. The cumulative diarrhea score increased exponentially 3 days after 5-FU challenge. The severity of diarrhea in the vehicle- and cyclosporine-treated animals plateaued after 7 days. Cyclosporine had no significant effect on the diarrhea severity.