Table II.
Variable | P300 (n = 30) | P600 (n = 30) | Control (n = 30) | P‡ |
---|---|---|---|---|
Cumulative morphine consumption | ||||
PACU | 8.03 (0.81)⁎† | 6.93 (0.83)† | 9.17 (0.38) | <0.001 |
2 h | 13.03 (1.30)⁎† | 11.37 (2.17)† | 14.77 (1.45) | <0.001 |
4 h | 20.63 (3.13)⁎† | 17.20 (3.12)† | 23.90 (3.20) | <0.001 |
6 h | 27.70 (3.01)⁎† | 22.67 (4.27)† | 32.60 (5.30) | <0.001 |
24 h | 40.80 (3.42)⁎† | 33.79 (5.77)† | 46.97 (6.67) | <0.001 |
VAS rest | ||||
PACU | 7.0 (0.7)⁎ | 5.50 (0.51)† | 7.20 (0.61) | <0.001 |
2 h | 6.03 (0.66)⁎ | 4.37 (0.49)† | 6.23 (0.56) | <0.001 |
4 h | 5.10 (0.75)⁎ | 3.57 (0.72)† | 5.30 (0.59) | <0.001 |
6 h | 3.20 (0.60)⁎ | 2.53 (0.7)† | 3.33 (1.0) | <0.001 |
24 h | 1.57 (0.6) | 1.47 (0.5) | 1.73 (0.9) | 0.39 |
VAS movement | ||||
PACU | 7.97 (0.5)⁎ | 6.9 (0.6)† | 8.27 (0.6) | <0.001 |
2 h | 6.80 (0.6)⁎ | 6.17 (0.6)† | 7 (0.8) | <0.001 |
4 h | 5.6 (0.7)⁎ | 4.97 (0.49)† | 5.83 (0.9) | <0.001 |
6 h | 4.23 (0.6)⁎ | 3.57 (0.6)† | 4.40 (1.0) | <0.001 |
24 h | 2.57 (0.6) | 2.43 (0.9) | 2.73 (0.9) | 0.40 |
Ramsay sedation score | ||||
PACU | 2.53 (0.51)⁎ | 2.87 (0.51)† | 2.33 (0.48) | <0.001 |
2 h | 2.40 (0.56)⁎† | 2.77 (0.43)† | 2.03 (0.32) | <0.001 |
4 h | 1.83 (0.53) | 1.93 (0.25)† | 1.60 (0.50) | 0.01 |
6 h | 1.50 (0.63) | 1.67 (0.48)† | 1.27 (0.45) | 0.01 |
24 h | 1.10 (0.31) | 1.23 (0.50) | 1.10 (0.31) | 0.30 |
Patient satisfaction score | ||||
PACU | 3.17 (0.37)⁎ | 2.73 (0.4)† | 3.30 (0.5) | <0.001 |
2 h | 2.87 (0.34)⁎ | 2.20 (0.4)† | 2.97 (0.18) | <0.001 |
4 h | 2.23 (0.4)⁎ | 1.87 (0.3)† | 2.40 (0.49) | <0.001 |
6 h | 1.63 (0.4) | 1.37 (0.4)† | 1.9 (0.60) | 0.001 |
24 h | 1.23 (0.43)⁎ | 0.93 (0.2)† | 1.43 (0.50) | <0.001 |
P300 = patients given 150 mg of pregabalin; P600 = patients given 300 mg of pregabalin; PACU = postanesthesia care unit; VAS = visual analogue scale.
Significantly different compared with P600 (P < 0.05).
Significantly different compared with control (P < 0.05).
1-way ANOVA test.