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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Lancet Diabetes Endocrinol. 2013 Sep 23;1(4):284–294. doi: 10.1016/S2213-8587(13)70111-6

Figure 4. CD2 expression levels on lymphocyte subpopulations.

Figure 4

Frozen PBCMs collected at baseline were analyzed for the mean fluorescence intensity (MFI) of CD2 by flow cytometry. Lymphocyte subpopulations were defined as follows: CD4 naïve (Tn): CD3+CD4+FoxP3−CD127hiCCR7+CD45RA+; CD4 central memory (Tcm): CD3+CD4+FoxP3−CD127hiCCR7+CD45RA−; CD4 effector memory (Tem): CD3+CD4+FoxP3−CD127hiCCR7−CD45RA−; regulatory T cells (Treg): CD3+CD4+FoxP3+CD127lo; CD8 Tn: CD3+CD8+CCR7+CD45RA+; CD8 Tcm: CD3+CD8+CCR7+CD45RA−; CD8 Tem: CD3+CD8+CCR7−CD45RA−; Naïve B cells: CD19+CD27−; Memory B cells: CD19+CD27+. Values are mean±SD.