Table 3.

Effect of administration of the aqueous macerate of G. dalenii, and D-AP7 on spontaneous locomotor activity in mice assessed on open field test

Treatments	Doses (mg/kg)	Crossings	Rearings
CON	-	115.3 ± 2.8	39.3 ± 2
D-AP7	50	111 ± 5	27.3 ± 1.9***
The aqueous macerate of G. dalenii	7.5	93.3 ± 3.3***	16.6 ± 2.2***
The aqueous macerate of G. dalenii + D-AP7	7.5 + 50	105.3 ± 3.7**	26 ± 3***
D-AP7	100	87.3 ± 3.1***	24 ± 2.7***
D-AP7	200	84.6 ± 3.4***	20.8 ± 2.1***

The aqueous macerate of G. dalenii and D-AP7 were administrated 24, 6 and 1 hour before the test. The values represent means ± SEM (n= 6 mice per group).

^**p<0.01;

^***p<0.001 compare to the negative control group (one way ANOVA followed by Newman-Keuls test).