Table 6.
Effect of E. speciosa extract on oxidative stress parameters in rats subjected to HCl/ethanol treatment.
Treatment (mg/kg): | Catalase | SOD | GSH | MDA |
(umol H2O2/min/mg) | (U/mg | (mmol/g × 10-3 ) | (mmol/g × 10-6 ) | |
- Normal rats | 10.44 + 1.35 | 12.46 + 0.37 | 9.13 + 0.50 | 10.45 + 1.19 |
- Negative control | 7.34 + 1.40 | 9.45 + 0.44 | 6.17 + 0.39 | 22.26 + 0.89 |
- E. speciosa 100 | 12.17 + 1.38* | 10.40 + 0.37 | 9.09 + 1.01* | 14.64 + 0.74** |
- E. speciosa 200 | 16.66 + 1.27** | 13.53 + 0.41** | 9.69 + 0.52** | 10.91 + 1.28** |
- Cimetidine 200 | 10.88 + 0.66 | 11.37 + 0.29** | 7.14 + 0.37 | 18.52 + 0.77* |
Statistically significant relative to the control, * (P<0.05); **(P<0.01); ***(P<0.001). SOD, superoxide dismutase; GSH, reduced glutathione; MDA, malondialdehyde. Each value is a mean from 6 rats ± SEM.