Table 9.
Effect of E. speciosa extract on oxidative stress parameters in rats subjected to Cold/restraint stress treatment
Treatment (mg/kg): | Catalase | SOD | GSH | MDA |
(umol H2O2/min/mg | (U/mg ) | (mmol/g × 10-3 | (mmol/g × 10-6 ) | |
- Normal rats | 5.13 + 0.90 | 8.26 + 1.02 | 6.99 + 0.12 | 3.08 + 0.59 |
- Negative control | 3.07 + 0.70 | 5.53 + 0.20 | 6.26 + 0.20 | 4.98 + 0.82 |
- E. speciosa 100 | 7.34 + 1.20* | 6.78 + 0.17 | 10.90 + 1.14* | 1.20 + 0.49* |
- E. speciosa 200 | 8.30 + 1.40* | 9.99 + 1.30* | 13.60 + 0.07* | 2.10 + 0.63* |
- Cimetidine 100 | 7.01 + 1.25* | 6.31 + 0.31 | 7.57 + 1.12 | 1.90 + 0.52* |
Statistically significant relative to the control, * (P<0.05); **(P<0.01); ***(P<0.001). SOD, superoxide dismutase; GSH, reduced glutathione; MDA, malondialdehyde. Each value is a mean from 6 rats ± SEM.