Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 1;141(7):1442–1452. doi: 10.1242/dev.103283

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014. Published by The Company of Biologists Ltd

PMC Copyright notice

Fig. 3. — Tissue-specific inactivation of Osr1 in the cap mesenchyme causes premature differentiation. (A-F) Immunofluorescent detection of Six2 (green) and pan-cytokeratin (red) in developing kidneys of Osr1^c/+;Six2-TGC^tg (A,C,E) and Osr1^c/-;Six2-TGC^tg (B,D,F) embryos at E11.5 (A,B), E12.5 (C,D) and E13.5 (E,F). Arrows in F indicate abnormal mesenchymal aggregates in Osr1^c/-;Six2-TGC^tg kidneys. Scale bars: 100 μm. (G-J) Whole-mount immunofluorescence detection of Cited1 (green, G,H) or Jag1 (green, I,J) and pan-cytokeratin (red) in cultured kidney explants. Arrows in J indicate ectopic Jag1 expression in the CM distal to the UB tips. Insets in the lower right-hand corners of I and J show higher magnification pictures of the respective boxed region. Scale bars: 200 μm.