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. 2014 Mar 18;6:44. doi: 10.3389/fnagi.2014.00044

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Copyright © 2014 Buga, Margaritescu, Scholz, Radu, Zelenak and Popa-Wagner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Patterns of gene expression after stroke in animal model. We distinguished two patterns of gene regulation, transiently upregulated (type B, expression recovered after the acute phase, green line) and “late-upregulated” (type C, expression went up after the acute phase; orange line). Please note that aged animals showed larger numbers of genes that were belatedly upregulated than the young animals. The young rats, in contrast, had a larger number of transiently upregulated including Cxcl1, S100a4, Runx3, Tgfbi, Vegfa, Vegfc.