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Sequencing for KRAS Mutation at Codon 12. Sequence chromatograms of KRAS codon 12. (A); Codon 12 of a control sample consisting of DNA deriving from normal pancreas. (B); Example for a KRAS mutation at codon 12 in an IPMN specimen with low-grade dysplasia showing the sequence change GGT > GAT. (C); and (D); show KRAS mutations in IPMN with moderate dysplasia, high-grade dysplasia and invasion respectively.
