TABLE 4.
Relative expression ratio by RT-qPCR of genes of HT-29 cells challenged with poly(I·C) only versus poly(I·C) plus PCa
| Immune gene protein | Expression ratio | 1/expression ratio | P value |
|---|---|---|---|
| TNF | 0.153 | 6.54 | 0.022 |
| FOS | 0.199 | 5.03 | 0.027 |
| CXCL10 | 0.225 | 4.44 | 0.013 |
| IL-17C | 0.228 | 4.39 | 0.024 |
| IL-29 | 0.265 | 3.77 | 0.019 |
| IL-28B | 0.292 | 3.42 | 0.042 |
| IL-8 | 0.335 | 2.99 | 0.000 |
| IRF1 | 0.352 | 2.84 | 0.007 |
| NFKB1 | 0.545 | 1.83 | 0.007 |
| NFKBIA | 0.564 | 1.77 | 0.031 |
a
Relative expression ratios were determined by RT-qPCR using REST 2009 (v2.0.13) analysis software. All genes selected were statistically significantly downregulated with a P value of <0.05.