FIG 4.

NRRL B-2354 acm gene insertion and impaired collagen adherence. (A) Schematic diagram of the acm gene in E. faecium NRRL B-2354 and clinical strain E. faecium TX0082. The genes are 99% identical in the coding regions (gray); however, a 1,059-bp insertion sequence (hatched lines) is located 52 bp from the start codon in NRRL B-2354. (B) E. faecium binding to type I collagen. Absorbance was significantly higher for TX0082 than for the other two strains (Tukey's honestly significant difference [HSD], P < 0.05). The averages ± SD of three replicates per strain are shown.