FIG 1.

M. tuberculosis antigen-specific IFN-γ responses are enriched in PFMC over PBMC from patients with TBP. M. tuberculosis antigen-specific IFN-γ responses were determined by ELISPOT assay in PBMC and matched PFMC. IFN-γ responses to ESAT-6 protein (A and B) and to an ESAT-6/CFP-10 peptide pool (C and D) were determined in PBMC and PFMC from patients with TBP (A and C) and from non-TBP patients (B and D). Each spot represents an individual data point. The differences between PBMC and PFMC were compared using the Wilcoxon matched-pair t test. ***, P < 0.0001. ns, statistically not significant. Please note the differences in the y axes.