TABLE 2.

Phenotypic drug susceptibility testing results for highly drug-resistant M. tuberculosis isolates collected from four multinational sites^a

Study site	Drug resistance (critical concn [mg/liter]) to the indicated antibioticb
	INH (0.1)		RIF (1.0)		MOX (0.25)		OFX (2.0)		AMK (1.0)		CAP (2.5)		KAN (2.5)
	No. of isolates		No. of isolates		No. of isolates		No. of isolates		No. of isolates		No. of isolates		No. of isolates
	R	S	R	S	R	S	R	S	R	S	R	S	R	S
India	104	7	103	8	98	13	100	11	94	17	88	23	99	12
Moldova	83	8	80	11	68	23	67	23	31	60	32	59	76	15
Philippines	88	21	78	33	34	75	35	75	13	98	9	91	16	95
South Africa	96	7	95	8	92	11	90	13	92	11	90	13	95	8
Total	371	43	356	60	292	122	292	122	230	186	219	186	286	130

^aIsolates were screened for phenotypic resistance (R, resistant; S, susceptible) on an MGIT 960 platform using WHO-recommended critical concentrations to define resistance.

^bINH, isoniazid; RIF, rifampin; MOX, moxifloxacin; OFX, ofloxacin; AMK, amikacin; KAN, kanamycin; CAP, capreomycin.