Table 1.

Duplications and syntenic breakpoints in the human genome compared with mouse

	Total analyzed			Duplication-positive counts*			Duplication-positive bases
	Number	bp	%†	Number	%	p-value‡	bp	%	p-value‡
Duplicated blocks	1,643	72,151,679	2.6	NA	NA	NA	NA	NA	NA
Break points	461	83,985,399	3.1	122	26.5	< 0.0001	20,030,062	23.8	< 0.0001
Between chromosomes	163	42,496,016	1.5	43	26.4	< 0.0001	7,265,961	17.1	< 0.0001
Different orientations	298	41,489,383	1.5	79	26.5	< 0.0001	12,555,425	30.3	< 0.0001

*A positive breakpoint contained ≥ 10 kb duplicated sequence (continuous sequence).^†Fraction of genome size (2,745,533,264 bp, which excludes highly duplicated pericentromeric and subtelomeric regions).^‡p < 0.0001, simulated value never exceeded observed in 10,000 replicates. NA, not applicable.