Impact of the different cefquinome dosage regimens on the proportion of cefotaxime-resistant Enterobacteriaceae in the fecal flora of rats before, during, and after treatment. ⧫, Patent-phase-adjusted dose (50 mg/kg); □, prepatent-phase-adjusted dose (5 mg/kg); , control untreated group. Data are means ± SDs. The arrows indicate the days of antibiotic administration.