FIG 3.

Replication of HRV-C replicons. H1-HeLa cells were electroporated with 10 μg or 1 μg of in vitro-transcribed RNA from subgenomic replicon constructs for HRV-C genotypes c15, c24, c25, and c11 and for the species A virus HRV16. Cells were treated with DMSO or HRV inhibitors at the concentrations shown, incubated at 33°C for 48 h, and assayed for Renilla luciferase activity. The 1-μg samples for the HRVc24 replicon were consistently at background levels and are therefore not included in the figure. Error bars represent the standard deviations of the means from triplicate tests.