TABLE 1.
Antibiotic susceptibilities of VIM- and NDM-producing K. pneumoniae strains expressed as MIC values and classification according to the clinical breakpoints defined by EUCASTa
| Antibiotic | VIM-KP T14789 |
VIM-KP ÖN-2211 |
NDM-KP IR8 |
NDM-KP IR62E |
||||
|---|---|---|---|---|---|---|---|---|
| MIC (mg/liter) | SIR | MIC (mg/liter) | SIR | MIC (mg/liter) | SIR | MIC (mg/liter) | SIR | |
| Aztreonam | 2 | I | 4 | I | >256 | R | >256 | R |
| Ciprofloxacin | >32 | R | 4 | R | >32 | R | >32 | R |
| Colistin | 0.125 | S | 0.125 | S | 0.125 | S | 0.125 | S |
| Daptomycin | >256 | – | >256 | – | >256 | – | >256 | – |
| Fosfomycin | 32 | S | 4 | S | 256 | R | 64 | R |
| Meropenem | >32 | R | 2 | S | 4 | I | >32 | R |
| Rifampin | >32 | – | >32 | – | 32 | – | >32 | – |
| Telavancin | 256 | – | 256 | – | 256 | – | 256 | – |
| Tigecycline | 2 | I | 1 | S | 2 | I | 3 | R |
| Vancomycin | >256 | – | >256 | – | >256 | – | >256 | – |
a
SIR, classification according to EUCAST definitions; S, susceptible; I, intermediate; R, resistant; –, not defined.