TABLE 2.

Compiled results from time-kill experiments with combinations that include meropenem, colistin, aztreonam, fosfomycin, and rifampin against VIM- and NDM-producing K. pneumoniae

^a+, synergy; MEM, meropenem; CST, colistin; ATM, aztreonam; FOF, fosfomycin; RIF, rifampin. Synergy (≥2 log₁₀ reduction in CFU/ml after 24 h compared with the most effective individual drug) and bactericidal effect (≥3 log₁₀ decrease in CFU/ml after 24 h compared with the starting inoculum) is depicted. Bactericidal effect is highlighted in gray.