TABLE 3.
Frequency of clinical findings among children hospitalized with community-acquired pneumonia and treated with aqueous penicillin G in 6 or 4 daily doses
| Clinical finding | Daily frequency (%) of indicated finding ona: |
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Day 0b |
Day 1 |
Day 2 |
Day 3 |
Day 4 |
Day 5 |
Day 6 |
Day 7 |
|||||||||
| 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | 6 daily doses | 4 daily doses | |
| Tachypnea | 77.8 (70/90) | 80.0 (92/115) | 69.2 (63/91) | 61.7 (71/115) | 56.5 (61/108) | 51.2 (64/125) | 54.5 (54/99) | 52.4 (55/105) | 50.0 (36/72) | 46.7 (35/75) | 40.4 (19/47) | 35.7 (20/56) | 33.3 (12/36) | 37.5 (15/40) | 33.3 (8/24) | 14.8 (4/27) |
| Fever | 65.7 (69/105) | 54.8 (74/135) | 36.3 (41/113) | 37.7 (43/114) | 30.2 (35/116) | 38.5 (50/130) | 29.0 (31/107) | 23.9 (28/117) | 24.7 (20/81) | 27.1 (23/85) | 19.2 (10/52) | 17.7 (11/62) | 9.8 (4/41) | 12.2 (6/49) | 8.3 (2/24) | 6.3 (2/32) |
| Chest retraction | 28.3 (34/120) | 31.9 (46/144) | 20.0 (24/120) | 15.3 (22/144) | 13.3 (16/120) | 11.1 (16/144) | 13.8 (15/109) | 7.4 (9/121) | 6.1 (5/82) | 5.6 (5/89) | 7.5 (4/53) | 1.5 (1/65) | 2.3 (1/43) | 0 | 4.2 (1/24) | 0 |
| Lower chest recession | 28.3 (34/120) | 27.1 (39/144) | 15.8 (19/120) | 11.1 (16/144) | 10.8 (13/120) | 10.4 (15/144) | 10.1 (11/109) | 6.6 (8/121) | 14.6 (12/82) | 10.1 (9/89) | 9.4 (5/53) | 1.5 (1/65) | 4.7 (2/43) | 0 | 4.2 (1/24) | 3.0 (1/33) |
| Nasal flaring | 3.3 (4/120) | 6.9 (10/144) | 3.3 (4/120) | 2.1 (3/144) | 2.5 (3/120) | 0.7 (1/144) | 1.8 (2/109) | 0.8 (1/121) | 1.2 (1/82) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cyanosis | 2.5 (3/120) | 0.7 (1/144) | 0.8 (1/120) | 0.7 (1/144) | 0 | 0.7 (1/144) | 0.9 (1/109) | 0 | 1.2 (1/82) | 1.1 (1/89) | 1.9 (1/53) | 0 | 0 | 0 | 4.2 (1/24) | 0 |
a
Values in parentheses indicate the number of children with the finding (numerator) and the total number of children examined for the finding (denominator). The denominator changed day by day as children were discharged.
b
Day 0 was the day when aqueous penicillin G treatment was initiated.