TABLE 2.
Determination of MICs of different antimicrobial agents for A. baumannii strains used in this study (mean values of duplicate assays)
| Antimicrobial agent | MIC (μg/ml) |
Difference in susceptibility (fold) |
|||
|---|---|---|---|---|---|
| ATCC 17978 wt | JPAB01 | JPAB01+pJPAB01 | ATCC 17978 wt vs JPAB01b | ATCC 17978 wt vs JPAB01+pJPAB01 | |
| Ceftazidime | 2 | 3 | 4 | 0.67 | 0.5 |
| Imipenem | 0.5 | 0.38 | 0.38 | 1.31 | 1.31 |
| Ciprofloxacin | 0.25 | 0.38 | 0.25 | 0.66 | 1 |
| Kanamycin | 3 | 1.5 | 2 | 2 | 1.5 |
| Tetracycline | 6 | 4 | 32 | 1.5 | 0.19 |
| Erythromycin | 12 | 6 | NDa | 2 | ND |
| Trimethoprim | 32 | 32 | ND | 1 | ND |
| Tigecycline | 1 | 0.5 | 0.5 | 2 | 2 |
| Colistin | 0.5 | 0.25 | 1 | 2 | 0.5 |
| Aztreonam | 16 | 2 | 16 | 8 | 1 |
| Aztreonam + PAβN | 4 | 0.5 | 2 | 8 | 2 |
| Nalidixic acid | 16 | 6 | 16 | 2.67 | 1 |
| Nalidixic acid + PAβN | 2 | 2 | 2 | 1 | 1 |
| Chloramphenicol | >256 | 32 | >256 | >8 | ND |
| Chloramphenicol + PAβN | 32 | 32 | 32 | 1 | 1 |
a
ND, not determined.
b
Values in bold indicate a difference in susceptibility of greater than twofold.