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Time- and concentration-dependent killing of E. coli BW25113 (wild type) in exponential phase. Cells were challenged with various concentrations (the MIC, 4× MIC, 8× MIC, etc.) of ADC111 (MIC of 2 μg/ml), NFT (MIC of 12.5 μg/ml), and ciprofloxacin (Cipro) (MIC of 0.01 μg/ml). Cell count was determined by plating on nutrient agar. The limit of detection is the x axis. Values are means ± SD. Data are representative of three independent trials. WT, wild type.
