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. 2014 Mar;88(6):3340–3352. doi: 10.1128/JVI.03380-13

FIG 5.

FIG 5

HIV isolates derived from elite suppressors are pathogenic in vivo and result in systemic CD4+ T cell depletion. Mononuclear cells were isolated from various tissues at necropsy. The percentage of T cells that express CD4 was calculated for each tissue. The bars represent the average for two animals. Results are from BLT mice infected with HLA*B57 elite suppressor-derived isolates (A), HLA*B57 chronic progressor-derived isolates (B), or noninfected BLT mice (C).