FIG 2.

Dectin-2 deficiency affects kidney histopathology during systemic infection with C. glabrata. Histopathological assessment of kidneys in uninfected Dectin-2^−/− (A), infected wild-type (B), and infected Dectin-2^−/− (C) (hematoxylin-and-eosin [H&E]-stained sections) and infected Dectin-2^−/− (D and E) (periodic acid-Schiff [PAS]-stained sections) mice. Representative localized lesions and C. glabrata colonies in the kidneys of Dectin-2^−/− mice are shown (C, D, and E). All observations of infected kidneys were performed at day 14 after intravenous injection with C. glabrata.