FIG 4.

YceG is necessary for resistance to reactive oxygen species and human cathelicidin. (A, C, and D) Growth of WT B. anthracis Sterne (black bars), transposon mutant (TN1, white bars), or insertional mutant (IM1, gray bars) for 16 h in H₂O₂ (A), hypochlorite (C), or cathelicidin (LL-37) (D). *, P < 0.05, **, P < 0.01, or ***, P < 0.001, from WT by one-way analysis of variance followed by Tukey's post hoc analysis. Data from at least three independent experiments are combined and presented as means ± standard errors of the means. (B) Survival of WT B. anthracis Sterne (black circles), the transposon mutant (TN1, white circles), or the insertional mutant (IM1, gray circles) after incubation with 0.05% H₂O₂ for 45 min. The experiment was repeated at least three times, and data from one representative experiment are presented as means ± standard deviations.