Skip to main content
. 2014 Mar;88(5):2951–2966. doi: 10.1128/JVI.03123-13

TABLE 1.

Prefusion F protein stability of CDV

CDV Temp of conformation switch (°C)a
No drug +3g
F-wt 58–60 65–67
F-L326A 50–52 60–62
F-L372G 44–46 51–53
F-L372A 51–53 60–62
F-P331A 50–52 60–62
F-S332A 50–52 60–62
F-V447T 51–53 61–63
a

Determined by detecting the temperature at which 50% of the F population was bound by the antiprefusion MAb and the other 50% was bound by the antitrigger MAb.