FIG 7.
Evaluation of antibody responses in mice i.m. vaccinated with rMuVΔSHΔV. BALB/c mice were i.m. immunized with PBS, rMuV, JL, rMuVΔSH, rMuVΔV, or rMuVΔSHΔV at 106 PFU/mouse and boosted at 22 days postvaccination with the same virus at 106 PFU/mouse. (A) ELISA results measuring total antibody titer at 14 dpb. Serum samples were collected at 14 dpb. The total antibody titer against MuV was measured through ELISA. (B) Neutralizing antibody titer at 14 dpb. Neutralizing antibody titers in serum samples collected at 14 dpb were measured through an rMuV-Luc-based neutralization assay. P values of <0.05 are shown.