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. 2004 Feb 25;5:4. doi: 10.1186/1471-2156-5-4

Table 3.

Comparison of SNP allele frequencies of the studied Caucasian sample with the data on Caucasians from databases and literature

Gene SNP Reference population Database or reference Data from a database or reference Caucasiansa
Frequencyb n Frequency n
APOE 1 American Caucasians [53] 0.33 220 0.357 1,862 0.48
2 American Caucasians dbSNP 0.33 24 0.399 1,839 0.64
Europeans from North Karelia, Finland dbSNP 0.4 24 0.399 1,839 0.84
3 European-Americans dbSNP 0.12 24 0.149 1,858 0.91
Caucasiansc HGVbase 0.16 152 0.149 1,858 0.81
Europeans from North Karelia, Finland dbSNP 0.23 24 0.149 1,858 0.37
4 European-Americans dbSNP 0.19 24 0.087 1,783 0.16
Caucasiansc HGVbase 0.08 152 0.087 1,783 0.87
Europeans from North Karelia, Finland dbSNP 0.04 24 0.087 1,783 0.25
COL1 α1 5 White women with Spanish ancestors [54] 0.13 256 0.154 1,856 0.36
6 American Caucasians [31] 0.187 637 0.188 1,855 0.98
ER-α 9 Australian females [55] 0.44 125 0.484 1,861 0.39
Greek males [56] 0.49 50 0.484 1,861 0.95
10 American females [57] 0.45 253 0.449 1,861 0.96
Finnish females [58] 0.42 322 0.449 1,861 0.38
11 SANGER 12 DNAs of Caucasian origin dbSNP 0.08 12 0.257 1,857 0.32
12 Australian females [55] 0.23 120 0.218 1,859 0.84
Slovenian females [59] 0.3 85 0.218 1,859 0.10
Caucasiansc dbSNP 0.27 31 0.218 1,859 0.59
13 Caucasiansc HGVbase 0.08 42 0.098 1,863 1.00
15 Caucasiansc dbSNP 0.18 31 0.203 1,863 0.90
IL-6 16 Caucasians dbSNP 0.5 31 0.434 1,860 0.58
English [60] 0.57 2,560 0.434 1,860 <0.01
Italians [61] 0.45 183 0.434 1,860 0.74
Spaniards [62] 0.56 118 0.434 1,860 0.01
Finns HGVbase 0.46 400 0.434 1,860 0.37
Finns HGVbase 0.48 50 0.434 1,860 0.62
Finns HGVbase 0.39 42 0.434 1,860 0.68
Finns [63] 0.45 400 0.434 1,860 0.60
LEPR 18 English males HGVbase 0.27 322 0.290 1,839 0.41
Caucasiansc [64] 0.28 56 0.290 1,839 0.98
Swedish males [65] 0.24 284 0.290 1,839 0.09
19 Swedish males [65] 0.15 284 0.182 1,776 0.21
20 Caucasiansc [64] 0.38 56 0.353 1,860 0.79
Caucasiansc dbSNP 0.4 42 0.353 1,860 0.64
English males HGVbase 0.36 322 0.353 1,860 0.77
TGF-ß1 26 Caucasiansc dbSNP 0.43 31 0.311 1,840 0.21
Caucasiansc HGVbase 0.26 42 0.311 1,840 0.59
27 Caucasiansc [66] 0.02 304 0.021 1,863 0.98
28 Danes [66] 0.027 302 0.008 190 0.33
29 Caucasianc female DZ twins [67] 0.25 1,802 0.274 1,852 0.08
TNFR2 31 UK Caucasians [68] 0.23 192 0.198 1,842 0.39
Germans [69] 0.25 94 0.198 1,842 0.33
Australians HGVbase 0.26 197 0.198 1,842 0.05
UCP3 32 American Caucasians [70] 0.21 56 0.265 1,767 0.49
Danes [71] 0.27 857 0.265 1,767 0.85
French [72] 0.22 894 0.265 1,767 0.01
33 Caucasiansc [73] 0.01 165 0.000 295 0.44
34 American Caucasians [70] 0.2 58 0.258 1,862 0.38
35 Caucasiansc [74] 0.5 501 0.447 1,863 0.04
36 Caucasiansc [73] 0.02 165 0.000 295 0.05
VDR 38 American Caucasians [75] 0.42 49 0.373 1,861 0.61
English [76] 0.4 241 0.373 1,861 0.47
Australians [77] 0.35 43 0.373 1,861 0.87
40 Caucasiansc dbSNP 0.42 107 0.419 1,860 0.94
English females [76] 0.44 241 0.419 1,860 0.61
Australian males [77] 0.47 39 0.419 1,860 0.66
Swiss [78] 0.39 197 0.419 1,860 0.49
French infants [79] 0.38 589 0.419 1,860 0.07
41 Caucasiansc dbSNP 0.48 31 0.408 1,859 0.51
French [80] 0.35 99 0.408 1,859 0.33
Australians [81] 0.41 68 0.408 1,859 0.94

For gene abbreviations and SNP designations see Table 1. a Present study. b Frequency of the allele corresponding to a minor allele in the present study. c Caucasians with unidentified ethnic background.