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. 2014 Mar 18;9(3):e91100. doi: 10.1371/journal.pone.0091100

Table 3. Pooled Analysis on Association between the C509T polymorphism and the RP risk.

C509T
Genetic Model Number of study Sample size Analysis Model I2 Test of Association(95%CI)
case control P OR
Dominant model 7 337 817 F 0 0.16 0.82 [0.62, 1.08]
Recessive model 5 171 600 F 5 0.21 0.74 [0.47, 1.18]
CT vs. CC 5 169 499 F 0 0.36 0.84 [0.58, 1.22]
TT vs. CC 5 113 344 F 0 0.10 0.63 [0.36, 1.08]
Ethnicity
Asian
Dominant model 4 176 465 F 0 0.68 0.92 [0.61, 1.38]
Recessive model 3 113 358 F 48 0.25 0.75 [0.46, 1.23]
CT vs. CC 3 84 251 F 0 0.92 1.00 [0.59, 1.70]
TT vs. CC 3 59 193 F 11 0.55 0.70 [0.39, 1.28]
Caucasian
Dominant model 3 161 352 F 0 0.12 0.73 [0.49, 1.09]
Recessive model 2 58 242 F 0 0.60 0.69 [0.18, 2.71]
CT vs. CC 2 84 251 F 0 0.99 1.00 [0.59, 1.70]
TT vs. CC 2 54 151 F 0 0.19 0.39 [0.10, 1.57]

Dominant model: CT+TT vs. CC; Recessive model: TT vs. CC+CT; Additive model: T vs. C; R, Random-effects model; F, fixed-effects model;