Table 1. Amino acid sequence comparison of salmon and human calcitonin.
Residue | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | |
Salmon Calcitonin | C | S | N | L | S | T | C | V | L | G | K | L | S | Q | E | L | H | K | L | Q | T | Y | P | R | T | N | T | G | S | G | T | P | -NH2 |
Human Calcitonin | C | G | N | L | S | T | C | M | L | G | T | Y | T | Q | D | F | N | K | F | H | T | F | P | Q | T | A | I | G | V | G | A | P | -NH2 |
Italic, underlined amino acids illustrate conservative substitutions. Amino acids in bold illustrate non-conservative substitutions. Disulfide bridge between C1-C7.