Table 1. Parameters used for electrospraying and details of the particulate products.
| No. | Process | Ccf a (w/v) | Fs b (mL/h) | Fc c (mL/h) | Cq d (%) | Diameter (μm) |
| M1 | Single | — | 1.0 | — | 0 | 1.35±0.67 |
| M2 | Coaxial | 3% | 1.0 | 0.4 | 7.64 | 1.69±1.13 |
| M3 | Coaxial | 3% | 1.0 | 0.7 | 10.71 | 1.74±1.02 |
| M4 | Coaxial | 3% | 1.0 | 1.0 | — | — |
| M5 | Coaxial | 5% | 1.0 | 0.7 | 16.67 | 1.85±0.83 |
a
Ccf represents the drug content in core fluid.
b
Fs represents the flow rate of sheath fluid that consists of 10% (w/v) PVP K25, 0.2% (w/v) SDS and 0.3% (w/v) sucralose in a mixed solvent system comprising water and ethanol (0.5:9.5, v:v).
c
Fc represents the flow rate of core fluid that consists of 10% (w/v) PVP and quercetin in a mixed solvent of DMAc and ethanol (4:6, v:v).
d
Cq represents the drug content in solid products, which is calculated according to the equation: Cq = (F c×C c)/{ [F s×(10%+0.2%+0.3%)]+ [F c×(10%+C c)]}, F s, F c, and C c represent the flow rates of the sheath and core fluids, and the drug contents in the core fluids, respectively.