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. 2014 Mar 18;9(3):e92089. doi: 10.1371/journal.pone.0092089

Table 5. List of the EAAT3 residues coordinating the three Na+ ions.

Outward Inward
Helix-Residue EAAT3 EAAT3
Na1 TM7 - G362 (O) Inline graphic Inline graphic
TM7 - N366 (O) Inline graphic Inline graphic
TM8 - N451 (O) Inline graphic Inline graphic
TM8 - D455 (O1) Inline graphic Inline graphic
TM8 - D455 (O2) Inline graphic Inline graphic
H2O Inline graphic Inline graphic
Na3 TM3 - Y98 (O) Inline graphic Inline graphic
TM3 - T101 (OH) Inline graphic Inline graphic
TM3 - T102 (OH) Inline graphic Inline graphic
TM7 - N366 (Oδ) Inline graphic Inline graphic
TM7 - D368 (O1) Inline graphic Inline graphic
TM7 - D368 (O2) Inline graphic Inline graphic
Na2 TM7 - T364 (OH) Inline graphic Inline graphic
HP2 - I406 (O) Inline graphic Inline graphic
HP2 - A408 (O) Inline graphic Inline graphic
H2O Inline graphic Inline graphic

The average Na+–O distances (in Å) are obtained from 5 ns MD simulations of the closed state in the outward and inward-facing conformations of EAAT3. Nature of the coordinating oxygens are indicated in parenthesis.