Table 2.
PURSUIT-SC study | GLM 200/100 mg at weeks 0 and 2 (%) | GLM 400/200 mg at weeks 0 and 2 (%) | Placebo (%) |
---|---|---|---|
Clinical response at week 6 | 51 | 54.9 | 30.3 |
Clinical remission at week 6 | 17.8 | 17.9 | 6.4 |
Mucosal healing at week 6 | 42.3 | 45.1 | 28.7 |
Notes: The recent Phase III PURSUIT clinical trials were the pivotal trials that led to regulatory approval of golimumab for ulcerative colitis.
Abbreviations: GLM, golimumab; PURSUIT, Program of Ulcerative Colitis Research Studies Utilizing an Investigational Treatment.