Table 3.
PURSUIT-Maintenance | GLM 50 mg every 4 weeks (%) | GLM 100 mg every 4 weeks (%) | Placebo (%) |
---|---|---|---|
Continuous clinical response through week 54 (among induction responders) | 47 | 49.7 | 31.2 |
Clinical remission at weeks 30 and 54 | 23.2 | 27.8 | 15.6 |
Mucosal healing at weeks 30 and 54 | 41.7 | 42.4 | 26.6 |
Notes: The recent Phase IIIPURSUIT clinical trials were the pivotal trials that led to regulatory approval of golimumab for ulcerative colitis.
Abbreviations: GLM, golimumab; PURSUIT, Program of Ulcerative Colitis Research Studies Utilizing an Investigational Treatment.