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. 2014 Mar 18;9(3):e92319. doi: 10.1371/journal.pone.0092319

Table 2. Clinical, physiological and blood parameters measured in patients included in the prediction set.

Category Method n Analytes
Clinical Anamnesis 10 Age, sex, length, weight, smoking, previous autologous or allogeneic hematopoietic stem cell transplantation, hypogammaglobulinemia, number of fever days prior to inclusion, presence of chills
Current medication Anamnesis 3 Corticosteroids, cytarabine, cyclosporin A
Physiology Examination 5 Body temperature, systolic and diastolic blood pressure, heart rate, peripheral oxygen saturation
Sampling Anamnesis 5 Fasting at the time of sampling, peripheral vein catheter, central venous catheter, port-a-catheter, sampling via peripheral vein
Blood cells and related variables Blood analysis 14 White blood cell counts (WBC), monocytes, neutrophils, basophils, eosinophils, lymphocytes, platelet counts (PC), erythrocyte particle counts (EPC), erythrocyte mean corpuscular volume (E-MCV), erythrocyte volume fraction (EVF), erythrocyte mean corpuscular hemoglobin concentration (MCH, MCHC), reticulocytes, hemoglobin
Complement Plasma analysis 5 Complement factor 3 (C3), C4, C4-binding protein (C4BP)-β, C4BP-β, total complement complex (TCC)
Coagulation and fibrinolysis Plasma analysis 17 Activated partial thromboplastin time (APTT), prothrombin time (measured as international normalized ratio, INR), coagulation factors II (prothrombin), V, VII, VIII, IX, X, XI, XII, von Willebrand factor, fibrinogen, anti-thrombin, D-dimers, plasminogen activator inhibitor-1 (PAI-1), protein C, protein S
Cytokines Serum analysis 8 Interferon-γ (IFN-γ, Interleukin-1 (IL-1), IL-6, IL-8, IL-10, IL-17, tumor necrosis factor (TNF), lymphotoxin (LT)
Acute phase proteins Serum analysis 16 C-reactive protein (CRP), haptoglobin, hemopexin, orosomucoid, serum amyloid A (SAA), α1-antitrypsin, α2-macroglobulin, ceruloplasmin, ferritin, hepcidin, pro-hepcidin, soluble transferrin receptor, total iron binding capacity (TIBC), transferrin, albumin, procalcitonin
Acute phase response Blood analysis 1 Erythrocyte sedimentation rate (SR)
Kidney function and electrolytes Serum analysis 13 Sodium (Na), potassium (K), Calcium (Ca), chloride (Cl), magnesium (Mg), phosphate (P), iron, urea, creatinine, cystatin C, NT-pro-brain natriuretic peptide (NT-pro-BNP), erythropoietin (EPO), renin
Liver Serum analysis 6 Aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), bilirubin conjugated, bilirubin total, γ-glutamyl transferase (γGT)
Organ stress and cell decay Serum analysis 13 Creatine kinase (CK), creatine kinase-muscle brain (CK-MB), troponin-T, lactate dehydrogenase (LDH), myoglobin, pancreatic amylase, total amylase, prostate specific antigen (PSA), free PSA, high mobility group box protein-1 (HMBG1), α-fetoprotein (AFP), urate, lactoferrin (plasma)
Metabolism Serum analysis 8 High density lipoprotein (HDL), low density lipoprotein (LDL), cholesterol, triglycerides, protein, leptin, adiponectin, glycosylated hemoglobin (HbA1c)
Metabolism Plasma analysis 1 Glucose
Hormones Serum analysis 10 Cortisol, T4 (tetraiodo-thyronine, thyroxine), free T4, T3 (triiodo-thyronine), free T3, thyroxine-binding globulin (TBG), thyroid-stimulating hormone (TSH), insulin-like growth factor-1 (IGF-1), estradiol, testosterone
Immunoglobulins Serum analysis 4 Immunoglobulin A (IgA), IgE, IgG, IgM
Total number 139