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. 2014 Mar 12;44(2):97–104. doi: 10.4070/kcj.2014.44.2.97

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Copyright © 2014 The Korean Society of Cardiology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4 — Gene expressions of IL-6 and TNF-α in rat lung tissues after bosentan treatment. mRNA expression of IL-6 was significantly decreased in weeks 1, 2, and 4 after bosentan treatment (A). mRNA expressions of TNF-α had significantly decreased on day 5, in weeks 1 and 2 after bosentan treatment (B). ^*p<0.05 significantly different from C group, ^†p<0.05 significantly different from M group. mRNA: messenger ribonucleic acid, IL: interleukin, TNF: tumor necrosis factor, C: control group, M: monocrotaline group, B: bosentan group.