Table 2.
Rates of thrombotic events in the two groups with different duration of dual antiplatelet therapy.
| Study ID | Total number in short duration group | Total number in longer duration group | Stent thrombosis | Myocardial infarction | Stroke | Revascularization |
Cerebrovascular death |
All-cause mortality | Death and myocardial infarction | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Short | Long | Short | Long | Short | Long | Short | Long | Short | Long | Short | Long | Short | Long | |||
| Gwon et al. 2012 (EXCELLENT trial) [6] | 722 | 721 | 6 (0.9%) definite 0 (0%) probable |
0 definite 1 (0.1%) probable |
13 (1.8%) |
7 (1%) |
3 (0.4%) | 5 (0.7%) | Target lesion revascularization 17 (2.4%) Target vessel revascularization 22 (3.1%) Any 43 (6.2%) |
Target lesion revascularization 18 (2.8%) Target vessel revascularization 22 (3.2%) Any 43 (6.2%) |
2 (0.3%) |
3 (0.4%) |
4 (0.6%) |
7 (1%) |
17 (2.4%) |
14 (1.9%) |
|
| ||||||||||||||||
| Hu and Wang 2012 [10] | 88 | 94 | Incidence 0.2% definite or probable | Incidence 0% definite or probable |
Incidence 0.2% |
Incidence 1% |
NA | NA | NA | NA | NA | NA | Incidence 2.6% | Incidence 2.3% | NA | NA |
|
| ||||||||||||||||
| Kim et al. 2012 (RESET trial) [7] | 1,059 | 1,058 | 2 (0.2%) definite or probable |
3 (0.3%) definite or probable |
2 (0.2%) |
4 (0.4%) |
6 (0.6%) | 6 (0.7%) | Target vessel revascularization 31 (3.9%) | Target vessel revascularization 27 (3.7%) | 2 (0.2%) |
4 (0.4%) |
5 (0.5%) |
8 (1%) |
7 (0.7%) |
11 (1.0%) |
|
| ||||||||||||||||
| Park et al. 2010 (REAL-LATE and ZEST-LATE) [8] | 1,344 | 1,357 | 4 definite (0.3%) | 5 definite (0.4%) | 7 (0.5%) |
10 (0.7%) |
4 (0.3%) | 9 (0.7%) | Any 26 (2.4%) | Any 36 (3.1%) | NA | NA | 13 (10%) |
20 (15%) |
17 (1.3%) |
27 (2.0%) |
|
| ||||||||||||||||
| Valgimigli et al. 2012 (PRODIGY) [9] | 983 | 987 | 7 definite (0.7%), 15 definite or probable (1.5%), 46 definite or probable or possible (4.7%) |
8 definite (0.8%), 13 definite or probable (1.3%), 38 definite or probable or possible (3.9%) | 41 (4.2%) |
39 (4%) |
14 (1.4%) | 21 (2.1%) | NA | NA | 37 (3.8%) |
36 (3.7%) |
65 (6.6%) |
65 (6.6%) |
94 (9.6%) |
88 (8.9%) |