Figure 7.

J_H usage in Igμ and Igγ transcripts from selected B cell populations in the blood of a normal, healthy human. The percent of sequences using J_H1 through J_H6 among in-frame reads cloned from the peripheral blood from immature, transitional, mature, memory IgD⁺, memory IgD⁻ B cells, and plasmacytes are displayed. All comparisons were made using χ²-test or Fisher’s exact test as appropriate. Significant differences among each fraction in the different mice are indicated by asterisks: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.