Table 2.

Univariate and multivariate analysis of overall survival in 57 HCC specimens

Variables		Univariate analysis			Multivariate analysis
	HR	95 % CI	P	HR	95 % CI	P
Age (years)	0.60	0.211–1.728	0.25
Gender	1.02	0.297–3.559	0.60
Histological grade	2.14	1.411–3.249	0.02*	1.38	0.823–2.333	0.22
Metastasis	2.61	0.710–9.655	0.12
Vein invasion	1.19	0.404–3.527	0.48
Tumor size	1.33	0.457–3.890	0.39
No. of tumor nodes	2.61	0.890–7.685	0.06
Capsular formation	0.86	0.298–2.502	0.50
HBsAg	1.79	0.582–5.549	0.23
Cirrhosis	1.52	0.466–4.980	0.34
Serum AFP level	1.24	0.438–3.536	0.44
KIF3B	4.26	2.14–10.84	0.006*	6.736	2.249–19.315	<0.01*
Ki67	2.28	1.41–4.82	0.03*	2.354	1.017–5.452	0.04*

Statistical analyses were performed by the Cox test analysis

HCC human hepatocellular carcinoma, HR hazard ratio, CI confidence interval, HBsAg hepatitis B surface antigen, AFP alphafeto protein

* P < 0.05 was considered significant