Table 1.
Mouse ESCs | Mouse EpiSCs | Human ESCs | CM ESCs | ||
---|---|---|---|---|---|
Morphology of colony | Small, dome | Large, flat | Large, flat | Large, flat | |
Growth factor dependency | LIF | + | − | − | − |
bFGF | − | + | + | + | |
TGFβ/activin | − | + | + | + | |
Marker expression | NANOG | + | + | + | + |
OCT3/4 | + | + | + | + | |
T (brachyury) | − | + | + | + | |
CER1 | − | + | + | + | |
EOMES | − | + | + | + | |
FOXA2 | − | + | + | + | |
GATA6 | − | + | + | + | |
SOX17 | − | + | + | + | |
Tolerance to single cell dissociation | + | − | − | − | |
Contribution in chimera | + | − | N/D | N/D |
N/D = not determined.