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The characters of mouse EpiSCs and mouse, human and CM ESCs.
| Mouse ESCs | Mouse EpiSCs | Human ESCs | CM ESCs | ||
|---|---|---|---|---|---|
| Morphology of colony | Small, dome | Large, flat | Large, flat | Large, flat | |
| Growth factor dependency | LIF | + | − | − | − |
| bFGF | − | + | + | + | |
| TGFβ/activin | − | + | + | + | |
| Marker expression | NANOG | + | + | + | + |
| OCT3/4 | + | + | + | + | |
| T (brachyury) | − | + | + | + | |
| CER1 | − | + | + | + | |
| EOMES | − | + | + | + | |
| FOXA2 | − | + | + | + | |
| GATA6 | − | + | + | + | |
| SOX17 | − | + | + | + | |
| Tolerance to single cell dissociation | + | − | − | − | |
| Contribution in chimera | + | − | N/D | N/D |
N/D = not determined.
