Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Mar 19;5:85. doi: 10.3389/fimmu.2014.00085

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Xu, Wang, Lackner and Veazey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Phenotyping and features of PD-1^HIGHCD4+ T cells in blood and mesenteric lymph nodes of adult rhesus macaques. (A) Representative plots of PD-1^HIGHCD4 T cells in PBMC and lymph node. (B) High co-expression of ICOS on PD-1^HIGH cells gated through CD4+ cells in lymph nodes. (C) Isotype control and IL-21 secretion (D,E) of CD4 T cell subsets from two healthy animal (JT40 and JJ80)-derived lymph nodes. Higher IL-21 secretion following mitogen stimulation of both PD-1^INT (blue gate) and PD-1^HIGH (green gates) by CD4+ T cells from lymph node cell suspensions [(C,D), gated on CD4+ T cells].