Table 3.
Peripheral T cell responses as measured by CD4+CFSElo proliferated cells for each individual with correlation to HLA-DQ genotype. Black boxes represent a response to the peptide with the SI ≥ 3. Gliadin epitopes are denoted as previously reported in the literature to be presented by HLA-DQ2 (α-I gliadin57–68 QLQPFPQPELPY, α-II gliadin62–73 PQPELPYPQPQL, and γ-1 gliadin139–152 PEQPQQSFPEQERP) or HLA-DQ8 (α-gliadin228–240 SGQGSFQPSQQNP and γ-gliadin65–79 FPQQPQQPYPQQPQQ with and without deamidation at p1 and p9). Three of the new-onset CD children responding to two or more peptides have the DQ2/2 genotype.