Table 6.

Multivariate logistic regression analysis for identification of independent clinical factors and biomarkers of predicting 6-month life dependence.

Variables	Adjusted odds ratio	95% Confidence interval	P
Clinical factors for predicting 6-month life dependence
Age	0.500	0.196~1.277	0.147
Pneumonia type	0.067	0.001~3.803	0.190
Charlson's comorbidity index	0.046	0.001~1.827	0.101
ICU stay	0.083	0.001~5.067	0.235
Hospital stay	0.861	0.670~1.105	0.240
MV day	1.134	0.851~1.512	0.390
Biomarkers of predicting 6-month life dependence
Lactate (mg/dL)
Day 1	0.909	0.737~1.127	0.385
Day 3	0.944	0.808~1.102	0.465
Albumin (g/dL)
Day 1	18.675	1.018~342.677	0.049
Day 3	0.415	0.016~10.551	0.595
Day 3 : Day 1	0.056	0.000~148.527	0.474
HMGB1 (pg/mL)
Day 1	1.003	0.999~1.006	0.099
Day 3	0.994	0.989~1.000	0.068

^aICU: intensive care unit; MV: mechanical ventilation; HMGB1: high-mobility group protein B1.