Table 3.

Allelic diversity of the 24 MIRU-VNTRs loci in 274 drug-resistant M. tuberculosis isolates from Sichuan, China.

Schemes of VNTR locus	VNTR locus	VNTR alias	No. of alleles	Range of repeats	Allelic diversity (HGI) for
					Beijing isolates (n = 190)	Non-Beijing isolates (n = 84)	All isolates (n = 274)
Discriminatory loci	424	Mtub04	6	0–4, 6	0.722	0.705	0.745
	577	ETR-C	5	2–6	0.111	0.159	0.126
	580	MIRU4	7	1–6, 8	0.185	0.65	0.367
	802	MIRU40	5	1–5	0.558	0.727	0.643
	960	MIRU10	6	0–5	0.589	0.596	0.627
	1644	MIRU16	6	0–5	0.664	0.689	0.673
	1955	Mtub21	9	1–9	0.706	0.73	0.803
	2163b	QUB-11b	15	0–10, 19–22	0.783	0.852	0.829
	2165	ETR-A	5	1–5	0.262	0.678	0.502
	2401	Mtub30	5	2–6	0.140	0.265	0.438
	2996	MIRU26	10	1–10	0.727	0.724	0.79
	3192	MIRU31	6	1–6	0.586	0.697	0.708
	3690	Mtub39	6	1–6	0.626	0.792	0.708
	4052	QUB-26	11	1–11	0.759	0.828	0.782
	4156	QUB-4156	7	0–7	0.605	0.479	0.571
Additional loci	154	MIRU2	3	1–3	0	0.07	0.022
	2059	MIRU20	2	1-2	0.031	0.069	0.043
	2347	Mtub29	4	2–5	0.052	0.093	0.064
	2461	ETR-B	3	1–3	0.031	0.488	0.236
	2531	MIRU23	7	1, 3–8	0.176	0.199	0.183
	2687	MIRU24	1	1	0	0	0
	3007	MIRU27	5	0–4	0.599	0.662	0.624
	3171	Mtub34	4	1–4	0.120	0.137	0.125
	4348	MIRU39	6	1–6	0.734	0.696	0.751

In bold: the HGI > 0.6.

The 12-loci-VNTR scheme was developed based on the highly discriminatory loci (HGI > 0.6) for all isolates. Both discriminatory and additional loci were from Supply et al. [31].