Figure 2.

Protective effect of pMSCs-HCM on H₂O₂-treated-caco2 cells. (A) H₂O₂ exerted cytotoxic effect on caco2 cell viability. Caco2 cells were incubated with H₂O₂ (100 μM) for 12 h. After H₂O₂ removal, cells were maintained in normal medium and viable cells were counted after 1, 3, 5, 7 days; º p < 0.05 versus caco2 cells at the corresponding times (n = 6); and (B) pMSCs-HCM has a better protective effect for H₂O₂-treated-caco2 cells than that of pMSCs-NCM. Caco2 cells were incubated with 100 μM H₂O₂ for 12 h; after drug withdrawal, cells were cultured in normal medium, pMSCs-NCM, and pMSCs-HCM. Five days later, viable cells were counted by trypan blue staining; º p < 0.05 versus NM; * p < 0.05 versus NM + H₂O₂; ^# p < 0.05 versus pMSCs-NCM + H₂O₂ (n = 10).