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. 2014 Jan 29;15(2):2157–2171. doi: 10.3390/ijms15022157

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© 2014 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 7. — Knockdown of XRCC2 decreased tumor growth in nude mice. (A) Tumor growth curve; (B) Tumor weight after mice were sacrificed; (C) Ectopic T84 xenografts in nude mice; and (D) Photograph of the dissected tumors. The effect of shRNA-XRCC2 on tumorigenicity was examined in nude mice. Mice were treated with either shRNA-XRCC2 or shRNA-SC. Radiation treatment (2 Gy) was given once every other day when tumor volume reached 100 mm³ in a total of 10 days. The tumor volume and tumor weight was examined for 28 days after exposure to radiation. The values are presented as the mean ± SD (n = 10). ** p < 0.01 compared with the control group.